Buses leave several times every hour from Santiago de Chile to La Serena. The trip takes 7 - 8 hours. Companies include Pullman Bus, TurBus and Flota Barrios. Available are regular buses, semi-cama and the first class salon-cama. Prices vary greatly.
You can see TurBus booking and timetables here:
The Most Frequently Asked Travel Questions about La Serena
Where To Stay & Best Hotels in La Serena - updated Apr 2024
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La Serena Travel Guide from Wikitravel. Many thanks to all Wikitravel contributors. Text is available under Creative Commons Attribution-ShareAlike 3.0, images are available under various licenses, see each image for details.
