Andijan ? Uzbekistan's fourth largest city, right in the heart of the vibrant but combustible Ferghana Valley.
Bukhara ? a legendary Silk Road capital, 2,500 years old, the historical center of which is a UNESCO World Heritage site filled with magnificent examples of monumental, medieval Islamic and Central Asian architecture.
Namangan ? the third largest city, at the northern edge of the Ferghana Valley.
Nukus ? the capital of Qaraqalpaqstan on the Amu Darya, surrounded by a region devastated by the environmental degradation wrought by the drying of the Aral Sea.
Samarkand ? the nation's second largest city, the whole of which is a UNESCO World Heritage site, home to the most famous Silk Road attraction of them all, the Registan.
Shakhrisabz ? a small city, whose historical center is a UNESCO World Heritage site for its impressive monuments from the Timurid Dynasty.
Termez ? the southernmost city near the border with Afghanistan, named by Alexander the Great's forces for the intense temperatures they found here (thermos = hot).
Several of these were once great trading cities on the Silk Road.
The Most Frequently Asked Travel Questions about Uzbekistan
Where To Stay & Best Hotels in Uzbekistan - updated Apr 2024
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Uzbekistan Travel Guide from Wikitravel. Many thanks to all Wikitravel contributors. Text is available under Creative Commons Attribution-ShareAlike 3.0, images are available under various licenses, see each image for details.